Bioinspired nanoparticles deliver gene editing to lower 'bad' cholesterol
Researchers from NUS Medicine and Tianjin Medical University General Hospital have developed bioinspired lipid nanoparticles that can deliver gene-editing machinery to the liver, effectively reducing 'bad' cholesterol (LDL) by over 20% after two doses. The study, published in the Journal of Controlled Release, showed fewer signs of inflammation and toxicity compared to other formulations.
Researchers from NUS Medicine and Tianjin Medical University General Hospital have developed bioinspired lipid nanoparticles that can deliver gene-editing machinery to the liver, effectively reducing 'bad' cholesterol (LDL) by over 20% after two doses. The study, published in the Journal of Controlled Release, showed fewer signs of inflammation and toxicity compared to other formulations.
Sources
- Phys.org — Bioinspired nanoparticles deliver gene editing to lower 'bad' cholesterol
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